Strong Performance Drives Further Upgrade to UCB’s 2026 Financial Guidance

Brussels (Belgium), 22 October 2026 – 07:00 (CET) – Regulated information - Inside Information – UCB today announced a further upgrade to its 2026 financial guidance, reflecting sustained business momentum and further progress against its long-term growth ambitions.

BIMZELX^® performance continues to strengthen based on robust volume growth across indications, faster patient conversion and higher retention rates. This is the result of focused investment, expanding access, a differentiated clinical profile and compelling BE BOLD data, which together are driving patient demand and market share gains. More favorable net pricing as a result of a more favorable channel mix is further strengthening performance and value per patient. CIMZIA^® also continues to deliver volume growth across markets despite a contracting anti-TNF market, while 340B dynamics have been more moderate, supported by optimized claims diligence and the impact of recent Orphan Drug Designation.

Higher revenue growth is expected to drive greater operating leverage and significant margin expansion.

Sandrine Dufour, CFO of UCB says: “The continued strong performance of BIMZELX^® and CIMZIA^® demonstrates the strength of our differentiated innovation strategy and our ability to translate innovation into sustainable growth. At the same time, excellence in execution is enabling us to convert robust revenue growth into greater operating leverage and profitability while continuing to invest in our future. This gives us confidence not only to raise our 2026 expectations but also in our ability to deliver meaningful impact for the those we serve."

The upgraded financial guidance excludes proceeds from the sale of a Priority Review Voucher (PRV), representing an additional low- to mid-single-digit percentage points uplift to revenue and adjusted EBITDA, respectively. 

UCB will publish the Full Year 2026 results and formal financial guidance for 2027 on February 25, 2027.

For further information, contact UCB: 

Investor Relations

Yvonne Naughton

T: +44.175.344.7521  

Yvonne.Naughton@ucb.com

Sahar Yazdian

T: +32.2.559.9137

sahar.yazdian@ucb.com

Corporate Communications

Laurent Schots 

T+32 2 559 92 64

laurent.schots@ucb.com     

About UCB

UCB, Brussels, Belgium (www.ucb.com) is a global biopharmaceutical company focused on the discovery and development of innovative medicines and solutions to transform the lives of people living with severe diseases of the immune system or of the central nervous system. With more than 9 000 people in approximately 40 countries, the company generated revenue of € 7.7 billion in 2025. UCB is listed on Euronext Brussels (symbol: UCB). 

Forward-looking statements

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Important factors that could result in such differences include but are not limited to: global spread and impacts of wars, pandemics and terrorism, the general geopolitical environment, climate change, changes in general economic, business and competitive conditions, the inability to obtain necessary regulatory approvals or to obtain them on acceptable terms or within expected timing, costs associated with research and development, changes in the prospects for products in the pipeline or under development by UCB, effects of future judicial decisions or governmental investigations, safety, quality, data integrity or manufacturing issues, supply chain disruption and business continuity risks; potential or actual data security and data privacy breaches, or disruptions of our information technology systems, product liability claims, challenges to patent protection for products or product candidates, competition from other products including biosimilars or disruptive technologies/business models, changes in laws or regulations, exchange rate fluctuations, changes or uncertainties in tax laws or the administration of such laws, and hiring, retention and compliance of its employees. There is no guarantee that new product candidates will be discovered or identified in the pipeline, or that new indications for existing products will be developed and approved. Movement from concept to commercial product is uncertain; preclinical results do not guarantee safety and efficacy of product candidates in humans. So far, the complexity of the human body cannot be reproduced in computer models, cell culture systems or animal models. The length of the timing to complete clinical trials and to get regulatory approval for product marketing has varied in the past and UCB expects similar unpredictability going forward. Products or potential products which are the subject of partnerships, joint ventures or licensing collaborations may be subject to disputes between the partners or may prove to be not as safe, effective or commercially successful as UCB may have believed at the start of such partnership. UCB’s efforts to acquire other products or companies and to integrate the operations of such acquired companies may not be as successful as UCB may have believed at the moment of acquisition. Also, UCB or others could discover safety, side effects or manufacturing problems with its products and/or devices after they are marketed. The discovery of significant problems with a product similar to one of UCB’s products that implicate an entire class of products may have a material adverse effect on sales of the entire class of affected products. Moreover, sales may be impacted by international and domestic trends toward managed care and health care cost containment, including pricing pressure, political and public scrutiny, customer and prescriber patterns or practices, and the reimbursement policies imposed by third-party payers as well as legislation affecting biopharmaceutical pricing and reimbursement activities and outcomes. Finally, a breakdown, cyberattack or information security breach could compromise the confidentiality, integrity and availability of UCB’s data and systems.

Given these uncertainties, the public is cautioned not to place any undue reliance on such forward-looking statements. These forward-looking statements are made only as of the date of this document, and do not reflect any potential impacts from the evolving event or risk as mentioned above as well as any other adversity, unless indicated otherwise. The company continues to follow the development diligently to assess the financial significance of these events, as the case may be, to UCB.

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